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NASA's Artemis II mission lifted off from Kennedy Space Center in Florida at 6:35 p.m. Eastern Wednesday. The mission aims to send four astronauts around the moon on a roughly 10-day journey.

Van Harris and his wife, Shirley, grew up a block away from each other in the Crown Heights section of Brooklyn. In this 2012 conversation they remember how they first met in the 1930s.

NPR's Leila Fadel talks with Jon Wertheim of Sports Illustrated about the players that stand out going into the U.S. Open tennis tournament, which starts this weekend.

The Washington Capitals star made history with a power play goal from the left faceoff circle — as Gretzky, who last set the record more than 25 years ago, looked on.

The Canadian government has expelled six diplomats in response to alleged criminal activities by Indian government agents. Canadian officials link the agents to homicides and acts of violence.

Secretary of State Marco Rubio and Secretary of Defense Pete Hegseth briefed lawmakers Wednesday on a threefold process for Venezuela's future.

A massive car bomb explosion in one of Hezbollah's Beirut strongholds left dozens of people wounded. It's the latest and deadliest response to the militant group's moves to support the embattled Syrian government's battle against rebel forces.

The Trump administration alleges the Voice of America is relaying Chinese propaganda. Founded at the dawn of World War Two, the government-funded news agency is independent by law.

Pete Gaynor has extensive experience at the local and state level dealing with natural disasters, but he faces something different now.

Top Afghan leaders are meeting President Biden Friday as the U.S troop withdrawal gains steam, talks remain deadlocked, and the Taliban continue to gain ground in Afghanistan.