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The successes and limits of America's drug war play out in New Mexico's Espanola Valley, an epicenter of heroin abuse. Despite a crackdown by law enforcement, the region continues to have the nation's highest per capita overdose death rate.

A Delaware judge has ruled that an edgy set of anti-smoking ads aimed at young people does not cross the line of vilifying tobacco companies or their employees. A Lorillard Tobacco Co. official said the company would appeal the ruling.

Attorneys for death row inmate Stanley Tookie Williams meet Thursday with California Gov. Arnold Schwarzenegger. They will argue for clemency for the Crips' co-founder and for commuting his sentence to life in prison without parole. Williams is scheduled to die by lethal injection on Dec. 13.

On the 25th anniversary of John Lennon's death, we listen to his introspective song, "In My Life," which was released in 1965. The former Beatle and peace activist John Lennon was murdered outside his New York City apartment at age 40 on Dec. 8, 1980.

Robert Moog, a pioneer of electronic music, has died. When he was a teenager, Moog started building theremins, and his early work in the development of electronic musical keyboards made his name synonymous with the word "synthesizer" through much of 1960s and '70s.

The Bush administration has proposed modestly higher fuel economy standards for pick-up trucks, sport utility vehicles and minivans. The plan would require the auto industry to raise standards starting in 2008 and to be completed by 2011. Left out of the standards: the largest SUVs, and cars.

The study makes use of lunar soil samples collected from Apollo 11, 12 and 17.

NPR's Puzzlemaster Will Shortz quizzes one of our listeners, and has a challenge for everyone at home. (This week's winner is Larry Davis from Santa Monica, California. He listens to Weekend Edition on member station KCRW.)

Supplies begin to reach earthquake-battered Pakistan. Eight U.S. helicopters are due Monday. More than 20,000 people are dead. U.N. official Vivian Tan and Ron Moreau of Newsweek tell Debbie Elliott what they're seeing.

New York City is increasing security on its subways after receiving what Mayor Mike Bloomberg calls a specific threat to mass transit in the coming days. At a press conference Thursday, he made note of an unusual "level of specificity" and said the threat originated overseas.