Joe Palca

The pharmaceutical giant Pfizer has begun testing a new coronavirus vaccine in the United States. The initial trial will involve 360 volunteers, and the first subjects have already received injections.

The vaccine was developed in a partnership between Pfizer and the German biotech company BioNTech. In addition to the U.S. trials, there will be some 200 patients enrolled in trials in Germany.

A panel of experts convened by the National Institute of Allergy and Infectious Diseases recommends against doctors using a combination of hydroxychloroquine and azithromycin for the treatment of COVID-19 patients because of potential toxicities.

"The combination of hydroxychloroquine and azithromycin was associated with QTc prolongation in patients with COVID-19," the panel said.

QTc prolongation increases the risk of sudden cardiac death.

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Being able to test for coronavirus infections is a critical component to reopening society — even a little bit — after the initial wave of COVID-19. So there is an urgent need for faster, cheaper tests than the ones available at present.

Two of the world's largest vaccine manufacturers are joining forces to develop a new vaccine to prevent COVID-19.

Usually, the pharmaceutical behemoths GlaxoSmithKline and Sanofi are competitors, but in a conference call with reporters, GSK CEO Emma Walmsley said the coronavirus pandemic represented "an unprecedented global health threat," and, therefore, required new ways of doing business.

Gilead Sciences is reporting some preliminary results from the use of its antiviral drug remdesivir in treating patients with COVID-19.

The study, published Friday by the New England Journal of Medicine, evaluated the response of 53 patients given remdesivir on a compassionate use basis.

Thirty-six showed clinical improvement, while eight got worse. Patients who were not on a ventilator tended to do better than those who were. Seven of the 53 died.

When our bodies are invaded by a virus, our immune systems make particular proteins called antibodies to help fight off infection.

Scientists working to quell the COVID-19 pandemic think it will be possible to figure out which antibodies are most potent in quashing a coronavirus infection, and then make vast quantities of identical copies of these proteins synthetically.

In an unusual move, the Food and Drug Administration today announced that is making it easier for doctors to try an experimental treatment for COVID-19 patients that uses plasma from people who had the disease and recovered.

There is scant evidence it works in people infected with the coronavirus, but the approach has been tried for other illnesses.

The federal government is now adding supercomputers to its tool set in the hunt for ways to stop COVID-19.

While health officials in the United States wait to see just how bad a public health challenge COVID-19 will pose, they still have to deal with an all-too-familiar challenge: flu.

It's been a bad flu season. Not the worst ever, but bad.

"It started very early this year," says Emily Martin, associate professor of epidemiology at the University of Michigan School of Public Health. She works with the Centers for Disease Control and Prevention collecting statistics about flu.

Viral infections can be very hard to treat. Just ask anyone who has a bad case of the flu.

But that's not deterring research groups around the world from looking for an effective therapy against the new coronavirus, although they know it won't be easy.

Right now scientists are trying to accomplish something that was inconceivable a decade ago: create a vaccine against a previously unknown virus rapidly enough to help end an outbreak of that virus. In this case, they're trying to stop the spread of the new coronavirus that has already infected tens of thousands of people, mainly in China, and given rise to a respiratory condition now known as COVID-19.

There's a mole on Mars that's making NASA engineers tear their hair out.

No, they haven't discovered a small, insectivorous mammal on the red planet.

The mole vexing engineers at the Jet Propulsion Laboratory in Pasadena is a scientific instrument known as the Heat Flow and Physical Properties Package, or HP3 — or just "the mole" — carried on NASA's InSight probe that landed on Mars a year ago.

It's not easy to treat viral infections. Just ask anyone with a bad cold or a case of the flu.

But scientists in Massachusetts think they may have a new way to stop viruses from making people sick by using what amounts to a pair of molecular scissors, known as CRISPR.

It's a gene editing tool based on a molecule that occurs naturally in microorganisms.

Tiny satellites are taking on a big-time role in space exploration.

CubeSats are small, only about twice the size of a Rubik's Cube. As the name suggests, they're cube-shaped, 4 inches on each side, and weigh in at about 3 pounds. But with the miniaturization of electronics, it's become possible to pack a sophisticated mission into a tiny package.

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